We're  
Siguru AI.

MLR approval needed an upgrade.

Slow MLR cycles. Stretched medical teams. Marketing held back.

We've been there and lived it.

So we created Siguru. Your AI assistant to support your team at every step of the MLR lifecycle.

It’s all about the people

Combining medical excellence with AI entrepreneurs, to create a better way to do MLR

Dan Bentley

Co-Founder & Chief Product Officer

At the age of 16, Dan sold his first technology company. He later spent several years in European pharma across marketing and omnichannel roles. During this time he saw the same challenge existed across the industry: marketing evolving faster than compliance processes.

Dan founded Siguru to help solve that gap. The rare combination of deep AI expertise with real-world pharma experience, Dan focuses on listening to customers and building a highly sophisticated yet easy to use AI solution for MLR approval processes.

Dr. Shazia Hasan

Medical Governance Expert

Shazia is a Consultant Pharmaceutical Physician and experienced senior medical signatory with deep expertise in oncology and promotional governance. Having held UK Medical Director and senior signatory roles in global pharma, she brings strong oversight of medical and regulatory standards.

At Siguru, Shazia provides senior governance insight to ensure high levels of rigour and accuracy.

Dr. Rina Newton

Commercial & Code Leader

Rina brings over 25 years of pharmaceutical compliance experience to Siguru’s team. A Healthcare Communiqué Award Winner (2025), she founded CompliMed in 2010, building it into a trusted compliance partner for pharmaceutical organisations across the UK before its merger with PharmaLex in 2020.

Rina is also Co-Founder of Code Clarity, founded on the principle of making compliance clear. At Siguru, she brings deep ABPI Code expertise and real-world review leadership to ensure the platform reflects how the MLR process truly operates.

Harry Ware

Founding Engineer

Harry is Siguru’s Founding Engineer, responsible for building the platform’s core architecture and intelligence from the ground up. He brings strong experience in scalable systems, resilience engineering and production infrastructure.

At Siguru, Harry leads development of the platform’s AI-driven compliance capabilities, ensuring it is reliable, secure and built to scale for highly regulated pharmaceutical environments.

Harry Bliss

Co-Founder & CEO

Harry Bliss is a serial entrepreneur and Co-Founder of Siguru AI. He previously built and scaled a B2B health-tech platform across 127 countries before exiting to a NASDAQ-listed company.

A former Forbes 30 Under 30 honouree, Harry has founded three successful start-ups and focuses on scaling Siguru, understanding customer needs and securing investment to build a world-class team.

Dr. Thom Van Every

Founding Advisory Board Member & ex-Medical Director

Thom is a UK-trained medical doctor, entrepreneur and former Medical Director in pharma, combining clinical leadership with business experience. He founded the UK’s first regulated online healthcare service, scaling it to acquisition, and later co-founded Lemonaid Health through to its acquisition in 2021.

Bringing a rare blend of medical expertise and entrepreneurship, Thom supports Siguru’s mission to modernise medical review and compliance in pharma.

Adam Smith

Founding Advisory Board Member

Adam is a senior commercial leader in life sciences SaaS and medicines information, currently Global Partnerships Director at Datapharm. He brings extensive experience across pharmaceutical data, healthcare technology and strategic partnerships.

At Siguru, Adam provides commercial insight and partnership expertise to help position the platform at the centre of the pharmaceutical information ecosystem.

Dr. Sarah Clarke

Code Compliance Leader

Sarah is an experienced ABPI physician Final Signatory with over 40 years advising pharmaceutical companies and agencies on navigating the realities and grey areas of the Code. Known for her practical, case-led approach, she has helped shape Code understanding across generations of Medical Affairs teams.

She is also the creator of Clarke’s Code Companion. At Siguru, Sarah brings real-world Code judgement to ensure the platform reflects how experienced signatories make defensible decisions.

Jean Woolcock

Code Compliance Expert

Jean brings over two decades of experience across the MLR process, supporting pharmaceutical organisations with their compliance. She later co-founded Code Clarity, built on the belief that compliance guidance should be simple, practical and actionable.

At Siguru, Jean brings scientific rigour and real-world MLR insight to ensure the platform reflects how reviews actually work.

Brad Bannerman

Operations Lead

Brad is Operations Lead at Siguru AI, responsible for building the operational foundations that enable the business to scale. With a background in engineering and delivery of safety-critical projects in the UK energy sector, he brings a structured, risk-aware approach to regulated environments.

At Siguru, Brad oversees legal, regulatory and operational alignment across the business, ensuring the platform is integrated responsibly into real-world pharmaceutical workflows.

David Walters

Commercial Lead

David is a seasoned commercial leader with over 30 years of experience across global, European and market-level pharmaceutical operations. He has led multi-billion-pound product portfolios, market access strategy and global launch programmes within leading pharma organisations.

At Siguru, David provides commercial insight and strategic challenge, helping ensure the platform delivers measurable impact across brand, medical and market access teams.

Amish Patel

Pharmaceutical Digital Marketing Specialist

Amish is a digital and channel strategy leader with extensive experience building global marketing capability in pharmaceutical organisations. He has led digital strategy and channel excellence initiatives across email, remote engagement and webinars.

At Siguru, Amish brings frontline marketing insight to ensure the platform works not only for reviewers, but also for the teams creating content every day.

Hannah Rentoul

Commercial Advisor

Hannah brings extensive UK pharma experience, With a background in market access, commercial strategy and marketing, she has led launches, lifecycle management and pricing negotiations within complex NHS environments.

At Siguru, Hannah brings practical insight from brand and market access teams, helping ensure the platform supports commercially effective content without compromising compliance.

Dr. Pundalik Nayak

Medical Lead

Pundalik is a Consultant Pharmaceutical Physician and ABPI Final Signatory with over 15 years’ experience in Medical Affairs across global and UK pharma. He has held senior medical roles across consumer health, rare diseases, vaccines and specialty care.

At Siguru, Pundalik brings front-line signatory experience to ensure the technology supports medical judgement rather than replacing it.

Gary Hibberd

Data Protection Expert

Gary brings over 40 years of experience in information security, governance and business continuity, helping organisations build resilient systems and strong security practices across regulated industries.

At Siguru, Gary ensures the platform follows gold-standard security protocols and robust governance frameworks, including ISO 27001, so pharmaceutical organisations can trust the platform meets the highest security expectations.

Built for Different Pharma Realities

Designed for every step of the content creation and review process.

Challenges

1. High material volumes strain capacity

2. Frustration from the marketing team due to a large content backlog

3. Significant spend across the entire MLR process

With Siguru

1. The same volume of materials can be approved quicker, freeing up capacity

2. Marketing teams can execute campaigns quicker and engage HCPs more effectively 

3. Enable efficiency across the marketing and medical teams, by saving time and costs

Challenges

1. Medical team are under significant pressure or high external review spend

2. Either produce less content due to the internal resource challenges or there’s a significant content backlog

3. Processes are individual rather than company wide, creating inconsistencies

With Siguru 

1. Reduce external spend and internal pressure on medical by faster checks, and compliant content from the outset

2. Enables faster, first-time-right submissions so marketing output increases without changing headcount

3. Standardises review processes across the organisation, driving consistency, visibility and alignment company-wide

Challenges

1. Multiple review rounds erode agency margins and extend project timelines

2. Compliance delays damage client trust and perceived agency performance

3. The content creators often have little compliance knowledge

With Siguru

1. Reduces review rounds through real-time compliance guidance

2. Accelerates approvals to improve client confidence and delivery

3. Enables every agency staff member to have a compliance expert

Principles That Guide Siguru

Built to support faster approvals without compromising medical or regulatory standards.

Client centric 

Built to solve real problems within your existing workflows.

Complete code checks

Comprehensive AI-assisted reviews, completed faster.

Smooth implementation

A dedicated onboarding team drives adoption across marketing and medical teams.

Clear limits

Understanding where AI adds value, and where expert judgement matters.

Built by experts

Siguru is built by people who understand regulated pharma environments.

Siguru's here to support medical and enable marketing.    

What you can expect to see

Pilot Siguru and see a measurable impact from the outset

Reduce MLR cycle time by 75-85%, (40 days to 7)

Cut review rounds by 40-60% on average (3.5 to 1.7)

Double first-round approvals 

Reduce agency rework costs by 20-30%

Cut signatory review time by up to 50%

Reduce time spent on hygiene checks by 80%

Revenue: Ability to develop improved marketing content  

Protection: Keep materials live and prevent withdrawals

Culture: Improve marketing and medical relations

Prevention: Reduce the risk of complaints

Capacity: Unlock time for medical teams

Confidence: Greater assurance at final sign-off

Curious how Siguru works? 

Book a demo, ask a question or explore a pilot.

Book a demo

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Ask a question

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Explore a pilot

Before making a commitment, explore how Siguru works with your team.